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Author

Martin W. Huellner

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Open access Sep 2026

Proteomic-guided targeted treatment of leukoencephalopathy with calcification and cysts.

Precision therapeutic approaches for rare neurological diseases are often hampered by a limited molecular understanding of the disease. Here, we report the first application of spatially-resolved proteomics to guide targeted treatment in a monogenic leukoencephalopathy. We investigated leukoencephalopathy with calcific...

Nils Briel, A. Köpp, Hanna Meister et al. · 0 citations
Clinical trial Open access Aug 2026

Treatment of multiple sclerosis with peptide-coupled red blood cells induces antigen-specific T regulatory cells.

Inducing antigen-specific immune tolerance is a long-standing aim in organ-specific autoimmune diseases including multiple sclerosis (MS). We developed a therapy based on autologous red blood cells (RBCs) as tolerizing carriers of autoantigens and tested these in an open-label, dose-escalation, phase Ib clinical trial...

Andreas Lutterotti, Thomas Ludersdorfer, M. Docampo et al. · 1 citation
Review Open access Aug 2026

Diagnostic value of positron emission tomography using amyloid-binding radiotracers for cardiac amyloidosis: a systematic review and meta-analysis

Amyloid PET demonstrates high sensitivity and specificity for CA detection, even though the evidence base remains limited in terms of the number and scope of available studies.

A. Walser, K. Bitos, Andreas A. Giannopoulos et al. · 0 citations

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