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Author

Mengchao Yu

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Aug 2026

PTX3 induces the expression of PD-L1 and promotes breast cancer immune escape.

It is demonstrated that PTX3 promotes immune evasion in breast cancer by upregulating PD-L1 by increasing the expression of the E3 ligase RNF216 and caused Beclin-1 degradation, which suppressed autophagy, thereby preventing autophagy-mediated PD-L1 degradation.

Li-Yuan Jing, Lun Jie, Jianxin Xu et al. · 0 citations

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