Open access
Oct 2026
Benchmarking single-cell foundation models reveals an advantage in the low-data regime for cell-type and disease-state prediction
Single-cell foundation models perform well on cell-type classification, but their value for disease-state prediction and their advantage over classical representations remains unclear. We benchmarked cell-representations from four foundation models using logistic regression, on 868 disease-prediction tasks (82 datasets...
Haya Benhayon, Michael M. Danziger, Danny Ben-Zvi et al.
· bioRxiv · 0 citations