Itaconimides combine an electron-deficient terminal methylene group with a succinimide framework, creating a reactive topology that differs from those of maleimides, citraconimides, and substituted α-alkylidene succinimides. This review critically examines annulation reactions of terminal-methylene itaconimides, define...
Mohammad Aslam, Priyanka Raju Thombal, Se-Ho Sun et al.· Catalysts· 0 citations
Chronic cutaneous wounds are often described as disorders of inflammation, infection, perfusion, or extracellular matrix turnover, yet these categories do not fully explain why a wound that initially detects injury fails to re-enter a coordinated program of repair. This Perspective proposes a unifying model in which th...
Muhammad Saeed Akhtar, Mohammad Aslam, M. M. Beg· Biomolecules· 0 citations
The adaptive plasma-membrane nanodomain code is defined as a testable, context-dependent relationship between measured organisational variables - size, density, stoichiometry, diffusion, residence time, lipid dependence and trafficking flux - and specified biochemical or physiological outputs under matched protein abun...
Sajid Ali, Muhammad Saeed Akhtar· Plant, Cell and Environment· 0 citations
Overall, CRISPR-Cas9 represents a vital platform for future pharmacological innovation, but its broad clinical use may require further validation of safety, efficacy, durability, and accessibility.
