N. Silvaggi

Toward an Understanding of the Mechanistic Differences Between the Hydroxylating and Desaturating Pyridoxal 5′‐Phosphate‐Dependent L‐Arginine Oxidases

Pyridoxal‐5′‐phosphate (PLP)‐dependent L‐arginine oxidases (PDAOs) catalyze 4‐electron oxidations of L‐arginine in the context of secondary metabolite biosynthesis. PDAOs are separated into two classes based on whether they hydroxylate or desaturate L‐arginine. A detailed mechanistic understanding of these enzymes will...