AI Networking Cookbook: Practical recipes for AI-assisted network automation and development
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It is demonstrated that CHD2 dosage bidirectionally regulates lysosomal function and autophagosome flux to set the tempo of neuronal maturation, and that CHD2 and lysosomal homeostasis constitute a critical molecular axis regulating the pace of cortical development across evolution and disease.
A co-maturation protocol that robustly generates glutamatergic neuronal networks containing hiPSC-derived microglia and induced the typical ramified microglia morphology and characteristic microglia-neuron interactions is presented.
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