O. El-khawaga

Mentha-mediated selenium nanoparticles attenuate adriamycin-induced chronic kidney disease via multi-target modulation of oxidative, inflammatory, and fibrotic pathways

Highlights • Mentha-mediated SeNPs protect against Adriamycin-induced chronic kidney injury via multi-target molecular modulation.• Green-synthesized SeNPs restore renal function and preserve kidney histoarchitecture in CKD rats.• SeNPs reduce oxidative stress and suppress apoptosis by inhibiting Bax and p53 signaling...

Systems pharmacology, structural modeling, and experimental validation reveal retinoic acid as a modulator of immune-fibrotic networks in chronic kidney disease.

Genetic variation in IL-6 rs1800796 and its association with non-Hodgkin lymphoma susceptibility in the Egyptian population

The results support the use of the IL-6 variation in the diagnosis and genetic screening of NHL but not for therapeutic choices, and suggest that individuals carrying the G allele may be at twice the risk of developing NHL compared with those carrying the C allele.