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Review Open access Oct 2026

CAR T-Cell Therapy in Hematological Malignancies: Mechanisms, Innovations, and Challenges

Chimeric antigen receptor (CAR) T-cell therapy has transformed the treatment of relapsed or refractory hematological malignancies, producing deep and durable responses in B-cell acute lymphoblastic leukemia, aggressive B-cell non-Hodgkin lymphomas, and multiple myeloma. Nevertheless, antigen escape, limited in vivo per...

Alaa A. A. Aljabali, Mohammad A. Obeid, A. Alqudah et al. · 0 citations
Jul 2026

Gastrodin mitigates cisplatin-induced cardiotoxicity in Swiss albino mice by restoring redox homeostasis and modulating the p62–Keap1–Nrf2 Axis

Gastrodin may have a protective activity against CP cardiotoxicity, primarily by restoring redox balance/energy status, suppressing inflammation and apoptosis, and modulating p62–Keap1–Nrf2 related gene expression.

A. Alqudah, E. Qnais, Yousra Bsieso et al. · 0 citations

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