Silybin-Loaded Chitosan–Gelatin Hydrogels as a Novel Strategy for MRSA-Infected Diabetic Foot Treatment: In Vitro, In Vivo, and In Silico Evidence
In vivo evaluation in an MRSA-infected diabetic foot wound model demonstrated accelerated wound closure and superior healing outcomes for both SB1 and SB2 compared with fusidic acid (Fucidin®) by day 12, suggesting that silybin-loaded CS–Gel hydrogels represent a promising therapeutic platform for the management of MRS...