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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

P. Cheng

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Open access Sep 2026

An in vitro System for Studying Osteochondrogenic Differentiation of Smooth Muscle Cells and Modeling Intimal Vascular Calcification

The osteochondrogenic differentiation assay results in a strong calcification phenotype together with a disease-associated CMC-like transcriptional state, providing a reliable in vitro model for mechanistic investigation of SMC phenotypic transition and prioritization of candidate regulators.

J. Monteiro, Matthew D. Worssam, Wen-Duo Gu et al. · 0 citations
Open access Aug 2026

Single-Cell Proteomics Uncovers Cell-Specific Proteins in Vascular Health and Marfan Syndrome Disease

The first human single-cell proteomic atlas of the aorta is established, altered FBN1 protein regulation in both human and mouse MFS is revealed, and single-cell proteomics is position as a transformative framework for decoding vascular plasticity and identifying actionable effectors in disease.

Junedh M. Amrute, Lihua Jiang, Nikhita Bolar et al. · 0 citations

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