Author

P. Pajukanta

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#protein folding Open access Oct 2026

Genome-wide analyses identify 60 loci associated with liver triglyceride content.

We performed a large-scale genome-wide association study meta-analysis of magnetic resonance imaging-derived liver triglyceride content across 71,488 European-ancestry participants from the UK Biobank, approximately doubling the sample size of previous genome-wide association studies1. We identified 60 independent loci...

O. Jamialahmadi, Shahir Mowlaei, K. Gelev et al. · Nature Genetics · 0 citations

Open access Oct 2026

Integration of single cell omics with biobank data discovers allele-specific trans effects of SREBF1 on adipocyte expression of nearly 100 genes

The heritability of epigenetic sites around SAT adipocyte marker genes is enriched for abdominal obesity, and that these cell-type markers are also enriched for central pathways of adipocyte function, indicating widespread cell-type level cis-type level trans effects on highly common CMDs.

M. G. Sukhatme, A. Kar, Seung Hyuk T. Lee et al. · Genome Medicine · 0 citations