Author

P. Shaw

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Open access Sep 2026

Circulating extracellular vesicle lipidomics identifies distinct signatures of amyotrophic lateral sclerosis and spinal muscular atrophy

Amyotrophic lateral sclerosis (ALS) is a heterogeneous neurodegenerative disorder lacking established biomarkers of underlying disease biology. Here, we identify lipidomic signatures of circulating extracellular vesicles (EVs) that distinguish ALS from neurologically healthy controls and related neuromuscular diseases....

V. Ricotti, A. Fogel, M. van den Bosch et al. · medRxiv · 0 citations

Open access Jul 2026

Circulating protein profiling identifies prognostic biomarkers in amyotrophic lateral Sclerosis

The utility of multiple proteins reflecting diverse biological pathways in refining survival stratification is indicates the utility of multiple proteins reflecting diverse biological pathways in refining survival stratification and highlights systemic factors in ALS progression.

H. Klimovski, M. Weinreich, A. Strange et al. · medRxiv · 0 citations

Open access Jul 2026

A proteomic signature for prognostic stratification in amyotrophic lateral sclerosis

This work indicates the utility of multiple proteins reflecting diverse biological pathways in refining survival stratification and highlights systemic factors in ALS progression, highlighting their potential role in measuring disease progression.

D. Lester, P. Piazza, E. Dellar et al. · medRxiv · 0 citations