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P. Shirote

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Sep 2026

Chitosan-Coated PLGA Nanoparticles Embedded Thermosensitive Intranasal In-Situ Gel of Withaferin-A for Enhanced Brain Targeting in Alzheimer’s Disease: Formulation, Optimization and PK-PD Evaluation

Treatment of chitosan-coated poly(lactic-co-glycolic acid) nanoparticles incorporated into a thermosensitive intranasal gel for enhancing brain exposure and the therapeutic potential of Withaferin-A in AD supports the potential of the CPNPs-loaded thermosensitive intranasal gel.

Rohit R. Todkar, P. Shirote, S. Mohite et al. · 0 citations

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