The zoonotic parasite Plasmodium knowlesi has emerged as a widespread cause of human malaria in Southeast Asia. We assembled a high-resolution transcriptome of zoonotic P. knowlesi across its intraerythrocytic developmental cycle and combined transcriptomics, quantitative proteomics and thermal stability measurements t...
Samuel Pazicky, Nicolas Aranciaga, Xia-Hong Gao et al.· bioRxiv· 0 citations
A chromosome-scale genome assembly for the K4-A7 cloned line of P. cynomolgi Berok is generated, establishing a high-resolution genomic foundation for comparative malaria biology, drug discovery, and the study of subtelomeric architecture, host adaptation, and lineage boundaries in primate Plasmodium.
A. Chua, Vipin Narang, Eric Jit Kai Lim et al.· bioRxiv· 0 citations
Exploring bacteriophage structural diversity is essential for understanding phage biology and for advancing phage-based therapies. Here, we determine the cryo-electron microscopy structure of Jabs, providing, to our knowledge, the first high-resolution view of a phage infecting the multidrug-resistant human pathogen My...
Christian Cambillau, Jun Hao Liew, Bernice Siu Yan Tan et al.· bioRxiv· 0 citations
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