A chromosome-scale Plasmodium cynomolgi Berok genome reveals a distinct subtelomeric architecture and a highly diverged primate malaria lineage

A. Chua Vipin Narang Eric Jit Kai Lim Sourav Nayak D. Glidden Peter Christensen Vaishnavi Chandramouli K. Shah Shu-Xuan Tan R. Suwanarusk K. G. Srinivasan A. Pain K. S. Tan Peter R. Preiser B. Russell Georges Snounou Laurent Rénia Zbynek Bozdech B. Lee Pablo Bifani

Aug 2026 · bioRxiv · 0 citations · 49 references

Biology

TL;DR

A chromosome-scale genome assembly for the K4-A7 cloned line of P. cynomolgi Berok is generated, establishing a high-resolution genomic foundation for comparative malaria biology, drug discovery, and the study of subtelomeric architecture, host adaptation, and lineage boundaries in primate Plasmodium.

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