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Open access Sep 2026

Anti-cancer Properties of Wogonoside on Oral Cancer Cells: An In Vitro Approach

Cancer is currently regarded as one of the leading causes of high rates of death and morbidity worldwide. One of the main causes of mortality globally is still oral cancer, which is more common in underdeveloped nations where tobacco and betel nut chewing are common. Treatment plans frequently include surgery, ta...

Xin-Nian Luo, Xin-Yi Luo, Jian Yin et al. · 0 citations
Open access Sep 2026

Single-cell lineage tracing in tumor organoids identifies expansion states depicting the origin and progression of lung adenocarcinoma

Introduction Only a subset of epithelial cells can initiate progressive lung adenocarcinoma (LUAD), yet the founder cell states that confer this competence remain poorly defined. Methods We established a barcoded KrasG12D, Trp53 loss mouse LUAD organoid model that couples 15-nucleotide lineage tracing with single-cell...

Wu-Tao Chen, Peng Li, He-Jian Zhang et al. · 0 citations

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