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Peng-Yi Li

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Open access Jan 2026

Aerosolized prostaglandin E1 improves oxygenation during one-lung ventilation: A dose-finding randomized controlled trial

Highlights • Nebulized PGE1improves oxygenation during OLV under 60% FiO2.• PGE1 reduces intrapulmonary shunt (Qs/Qt) without increasing PPCs.• The 0.3 μg/kg dose provides the greatest oxygenation benefit.• High dose PGE1 is associated with lower CPIS (exploratory, surrogate endpoint).• Hemodynamic monitoring is advise...

Peng-Xi Li, Xin-Yang Hu, Peng-Yi Li et al. · 0 citations

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