AI Networking Cookbook: Practical recipes for AI-assisted network automation and development
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Clinical observations have supplemented findings by Braak and colleagues demonstrating that, like impaired sense of smell, olfactory bulb involvement by Lewy pathology is a common early feature in Parkinson disease.
Polyamines (PAs) are evolutionarily conserved metabolites that connect protein quality control with lysosomal, mitochondrial, and redox homeostasis. Their metabolism is situated at a critical intersection of cell-sustaining and neurodegenerative pathways. Here, we synthesize evidence across Alzheimer's disease, Parkins...
OA is established as a striatal neuromodulator that interacts with other neurotransmitter systems and preferentially potentiates direct-pathway transmission, with major relevance to Parkinson's disease and other movement disorders.
While these multimodal biomarkers offer unprecedented mechanistic insights into disease progression and therapeutic response, their ultimate value depends on successful clinical translation, it would be essential for the field to prioritize standardized acquisition protocols, automated post-processing pipelines, and ac...
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