Author

Pierre D'Haese

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Open access Jul 2026

Anti‐amyloid immunotherapy and brain volume trajectories in early‐onset versus late‐onset Alzheimer's disease

Accelerated brain volume loss has been observed following trials of anti‐amyloid beta immunotherapy (AAT); however, there is limited understanding of this paradoxical phenomenon in early‐onset Alzheimer's disease (EOAD) versus late‐onset Alzheimer's disease (LOAD).

R. Mehta, Methasit Jaisa-aad, Camila Vieira Ligo Teixeira et al. · Alzheimer's & Dementia · 0 citations

Review Oct 2026

Focused ultrasound blood-brain barrier opening: a review of post-procedure MRI outcomes.

INTRODUCTION Focused ultrasound (FUS) blood-brain barrier opening (BBBo) is an incisionless technique that facilitates cerebral drug delivery by temporarily increasing BBB permeability. Clinical trials have shown that FUS produces reversible BBBo and is feasible in humans. There are currently no standardized imaging pr...

Suzanne LeBlang, R. Mehta, Pierre D'Haese et al. · Expert Review of Neurotherap... · 0 citations

Review Jul 2026

Neuromodulation in Alzheimer's disease: a review with illustrative pilot data using focused ultrasound.

A narrative review of evidence across neuromodulation approaches to define principles of circuit engagement in AD and discuss a network-based rationale for ultrasound interventions support a framework in which FUS may help reshape pathological network states that emerge prior to irreversible neurodegeneration.

Marc W. Haut, Camila Vieira Ligo Teixeira, M. Ranjan et al. · Biological Psychiatry · 0 citations