A phosphoproteome atlas of human cell lines reveals the landscape of kinase activity.
Protein phosphorylation orchestrates cellular signaling and controls most biological processes, with its dysregulation driving diseases, notably cancer. Comprehensive, high-throughput phosphoproteomics remains limited by detection sensitivity, data completeness and computational bottlenecks, especially in low-input set...
Claire Koenig, Hayoung Cho, K. B. Emdal et al.
· Nature Structural & Molecula... · 1 citation