Differential genetic risk patterns linking adipose distribution to multiple cardiometabolic diseases and reveals interconnected metabolic, immune, and vascular mechanisms are delineated, providing a genetic framework for cardiometabolic and cardiovascular risk assessment and the prioritization of potential therapeutic...
Qian Wu, Fan Yang, Qi An et al.· Journal of the American Hear...· 0 citations
This study provides a multi-scale characterization of the shared genetic architecture between MD and intrinsic brain functional connectome organization, revealing that shared genetic signals between MD and brain functional systems are distributed across multiple functional levels and converge at the molecular level.
Qi An, Ying Zhai, Wen-Jie Cai et al.· Progress in Neuro-psychophar...· 0 citations
The findings reveal partial genetic overlap between altered brain aging and diverse psychiatric disorders, providing an integrative cross-modality perspective on the shared genetic influences and related biological pathways linking brain aging and psychiatric vulnerability.
Qi-Yu Zhao, Qi An, Wen-Jie Cai et al.· Molecular Psychiatry· 2 citations
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