Transcriptional reprogramming with endogenous cis- and trans-elements for efficient food protein expression from safe substrates in Komagataella phaffii.
Sustainable economy and social development require a paradigm shift in the modes of production of edible proteins. Komagataella phaffii is a preferred host for food protein expression. However, its methanol-dependent production mode and host improvement with exogenous bioelements pose challenges for the manufacturing a...