A Meta-Analysis of Animal Experiments on CRISPR-Cas9 Gene Editing for Hereditary Blood Disorders: Efficacy Assessment and Challenges in Hematopoietic System Reconstitution
CRISPR-Cas9 has demonstrated high initial editing efficiency in animal models of inherited hematological disorders and has successfully produced phenotypic improvements, manifested as an increased percentage of red blood cells in mice after transplantation, suggesting its potential therapeutic prospects for correcting...