#machine learning
Apr 2026
Transcriptomic Models for Immunotherapy Response Prediction Show Limited Cross-cohort Generalisability
Immune checkpoint inhibitors (ICIs) have transformed cancer therapy; yet substantial proportion of patients exhibit intrinsic or acquired resistance, making accurate pre-treatment response prediction a critical unmet need. Transcriptomics-based biomarkers derived from bulk and single-cell RNA sequencing (scRNA-seq) off...
Yu-Heng Liang, Lucy Chhuo, A. Argha et al.
· arXiv.org · 0 citations