Author

R. Bader

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Mediators of paramutation affect chromatin looping at the b1 locus

FAIRE analysis on these mutants suggests that the occurrence of physical interactions appears not dependent on a particular chromatin state, and a B-I -like multi-loop structure mediates high b1 expression.

M. Louwers, R. Bader, R. van Driel et al. · 0 citations

MOP1 affects DNA methylation, nucleosome occupancy, histone modifications and chromatin conformation at the b1 allele involved in paramutation

The results uncover an intricate interplay between active and silent epigenetic features present at the b1 locus in a mop1 background, resulting in elevated expression of B’, concluding that MOP1 is essential to maintain the B’ silent chromatin state.

M. Louwers, M. Haring, R. Bader et al. · 0 citations