Author

R. T. Raines

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#protein folding Sep 2026

Abstract B095: Discovery of treatment-associated peptide antigens for targeted immunotherapies in pancreatic ductal adenocarcinoma

This work provides a framework for identifying actionable treatment-induced peptide antigens and supports rational combination strategies pairing KRAS/RAS inhibitors with T cell-based immunotherapies, including BiTE, CAR-pMHC, TCR-T, and cancer vaccine approaches.

Wei-Xi Kang, Allison Glynn, Harshabad Singh et al. · Cancer Research · 0 citations

Open access Aug 2026

Quantum chemical profiling of the electronic structure and hydrolytic stability of modified ribonucleosides

Chemical modifications to RNA play essential roles in regulating structure, stability, and biological function, yet a unifying physicochemical framework for understanding how these structural modifications perturb the underlying electronic landscape and influence intrinsic reactivity remains lacking. Here, we apply den...

Volga Kojasoy, R. T. Raines · Physical Chemistry, Chemical... · 0 citations