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Author

R. Turakulov

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Review Aug 2026

Clinical significance of lncRNA-miRNA axes in ischemic stroke: Diagnostic value, prognostic relevance, and therapeutic potential.

Ischemic stroke and subsequent reperfusion injury are major causes of mortality and long-term neurological disability, driven by complex mechanisms of excitotoxicity, oxidative stress, neuroinflammation, endothelial dysfunction, and blood-brain barrier disruption. Increasing evidence indicates that long non-coding RNA...

Amr A. El-Sehrawy, I. Sapaev, O. Nematov et al. · 0 citations
Review Sep 2026

NRF2-Regulated Ferroptosis in Breast Cancer: Mechanisms, Resistance, and Therapeutic Opportunities.

The molecular mechanisms by which NRF2 regulates ferroptosis, including KEAP1-NRF2 signaling, metabolic rewiring, iron homeostasis, lipid remodeling, and crosstalk with p53 and other stress-response pathways are summarized.

S. Mohammad, A. Vasudevan, Samreet Raizal Rodrigues et al. · 0 citations
#protein folding Open access Aug 2026

SIRT1 deacetylates GAPDH to drive microglial glycolysis and neuroinflammation.

SIRT1–GAPDH signaling represents a post-translational axis linking sirtuin activity directly to glycolytic enzyme function, distinct from SIRT1's traditional transcriptional roles and serving as a viable molecular checkpoint in microglial immunometabolism.

Chou-Yi Hsu, I. Sapaev, O. Nematov et al. · 0 citations

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