It is established that an organized microtubule network is present in Xenopus spermatids and shares key architectural and molecular hallmarks of the mammalian manchette, and a large structural heterogeneity of spermatid microtubules is uncovered, suggesting an internal reinforcement mechanism necessary for extensive nu...
C. Callens, M. P. Benoit, Florian Berger et al.· bioRxiv· 0 citations
This study showed that gonia cells represent an immature, proliferative, and highly plastic germ-cell population, with a transcriptomic program largely shared between the male and female developmental pathways, and characterized that early oocyte development is associated with activation of meiotic, cell-cycle, proteos...
Yan-Wen Lian, I. Boutet, Anne-Sophie Le Port et al.· Marine Biotechnology· 0 citations
During spermiogenesis, early round spermatids differentiate into specialized spermatozoa through an extensive reshaping of the nucleus driven by coordinated cytoskeletal and chromatin-based mechanisms. In mammals, this process critically relies on the transient manchette, a microtubule-based structure that remodels the...
C. Callens, M. Benoît, Florian Berger et al.· bioRxiv· 0 citations
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