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Rachelle Nelson Zoni

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#protein folding Open access Oct 2026

Endothelial Matrin-3 Limits Cellular Senescence and Lipid Dysregulation to Protect Against Murine Atherosclerosis.

It is found that Matrin-3 silencing induces endothelial senescence, characterized by reduced cell proliferation, increased senescence-associated β-galactosidase activity, and impaired mitochondrial function in vitro, and that endothelial Matrin-3 deficiency is associated with both local vascular alterations and systemi...

Xiao Cheng, Fatema Yeasmin Tanni, Rachelle Nelson Zoni et al. · 0 citations
Open access Sep 2026

NAE1-Dependent Protein Neddylation Preserves Endothelial Identity and Vascular Integrity

Background Endothelial dysfunction is a central driver of cardiovascular and inflammatory diseases, yet the post-translational mechanisms that preserve endothelial homeostasis remain incompletely understood. Protein neddylation, the covalent conjugation of a ubiquitin-like modifier, regulates diverse cellular processes...

Rachelle Nelson Zoni, Fatema Yeasmin Tanni, Chang-Min Lee et al. · 0 citations

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