Open access
Oct 2026
Distinct regulation across the transcription cycle drives mitotic transcriptional silencing
In most organisms, as cells enter mitosis, transcription is globally silenced. While individual studies have shown that each stage of the transcription cycle can be modulated during mitosis, how initiation, elongation, and termination are temporally and kinetically regulated to ensure transcriptional silencing remains...
Paola Gaetani, Alexandra Tavares, Tiago Paixão et al.
· bioRxiv · 0 citations