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Open access

Transcription termination factor 2 (TTF2) prevents premature rRNA synthesis during mitotic exit

Catarina Pedro Laura Tovini Catarina Peneda Mia Maesano Krapinec Raquel A. Oliveira
Oct 2026 · Life Science Alliance · Vol 9 · 0 citations · 36 references
Medicine

Abstract

TTF2 restrains RNA Polymerase I reactivation at mitotic exit, and its loss triggers premature rRNA synthesis and nucleolar fragmentation.

DOI PubMed Semantic Scholar
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