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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

Rob M. Scrutton

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3 papers indexed here

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Open access Sep 2026

Mapping high resolution, multidimensional phase diagrams of near-physiological protein condensates

ExVivo PhaseScan is established as a versatile tool for dissecting the physicochemical and pathological regulation of condensates, with potential to inform therapeutic strategies for diseases driven by aberrant phase transitions.

Tanushree Agarwal, Tomas Šneideris, Fabian Svara et al. · 0 citations
#protein folding Open access Sep 2026

Mechanistic Interpretability of Protein Language Models Reveals Encoded Structural and Functional Properties of Intrinsically Disordered Proteins

It is shown that ESM-2 exhibits reduced attention on disordered regions, yet still encodes meaningful biological signals, and that both the radius of gyration and individual dynamic contact maps, key characteristics of IDPs, can be obtained from the model logits and embeddings.

Lauren Naworski, Lydia L. Good, Rob M. Scrutton et al. · 0 citations
#protein folding Open access Aug 2026

Quantifying molecular specificity in excipient-driven antibody solubilization

It is shown that excipient-mediated solubilization of therapeutic antibodies is markedly molecularly specific, and the integration of high-throughput experimentation with molecular feature analysis offers a foundation for improving the understanding and prediction of antibody-specific formulation behavior.

Zexiang Han, Nadia A. Erkamp, Rob M. Scrutton et al. · 0 citations

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