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Ruby A. Escobedo

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Open access Aug 2026

A One-Shot Multivalent Live-Attenuated Candidate Influenza Vaccine against Divergent Zoonotic H5N1 Clades

The development and implementation of this multivalent LAIV as a broadly protective pan-H5N1 LAIV for pandemic preparedness are supported and the feasibility of developing and implementing this multivalent LAIV as a broad protective pan-H5N1 LAIV against divergent H5N1 viruses for human use is demonstrated.

Ahmed M. Elsayed, Ramya S. Barre, Arash Rahmani et al. · 0 citations
Open access Aug 2026

Mutations in SARS-CoV-2 Nsp1 are critical determinants of viral pathogenicity in mice

The reduced pathogenicity of rSARS-CoV-2 Nsp1 mutants highlights the potential for targeting Nsp1 for rational design of viral inhibitors and development of live-attenuated vaccine strategies as effective prophylactic and therapeutic treatments to combat SARS-CoV-2 and possibly other CoV infections.

Nathaniel Jackson, Fu-Chun Zhou, Anastasija Cupic et al. · 0 citations

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