Author

Rui Zhang

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Open access Sep 2026

Prediction of pathological complete response after neoadjuvant therapy in breast cancer using pretreatment core biopsy pathology reports: a pathology-report-driven model with exploratory clinical-laboratory fusion

Pathological complete response (pCR) after neoadjuvant therapy is an important response endpoint in breast cancer. We investigated whether routinely generated pretreatment core biopsy pathology reports could support pCR prediction and whether clinical, preoperative laboratory, and treatment information provided increme...

Rui Zhang, L. Qi, Bin Li et al. · Frontiers in Oncology · 0 citations

#protein folding Open access Sep 2026

Multidimensional neuropsychological heterogeneity in obstructive sleep apnea: deep clinical phenotyping in a single-center cohort, population proteomic context, and depressive-burden risk stratification

The findings support a multidimensional framework integrating differentiated clinical associations, a non-random general-population proteomic context, human functional transcriptomic context, and encouraging cross-setting depressive-burden risk ranking, while absolute probabilities remained less stable; OSA-specific mo...

Xiao-Yu Wang, Yi-Run Jiang, Lei-Lei Yu et al. · Frontiers in Immunology · 0 citations