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Open access Sep 2026

Mechanistic hazard differentiation of cerium oxide and barium sulfate nanoparticles using a human-relevant lung model.

Increasing regulatory pressure to reduce animal testing has accelerated the development of New Approach Methodologies (NAMs) for hazard assessment. This study employed a Calu-3/monocyte-derived macrophages (MDMs) co-culture at the air-liquid interface to assess the biological effects of cerium oxide (CeO₂) and barium s...

Isidora Loncarevic, Seyran Mutlu, Roman M. Fortunatus et al. · 0 citations
#protein folding Open access Sep 2026

Characterization of Single Ribosomes and Virus Particles with Large-Diameter Perfringolysin O Nanopores

The self-assembly of the cholesterol-dependent cytolysin Perfringolysin O (PFO) into stable transmembrane nanopores composed of 46 ± 9 monomers is reported, enabling, for the first time, resistive-pulse-based characterization of intact virus particles and ribosomes with a biological nanopore.

Andela Vracar, Veneta Salyahetdinova, S. Balog et al. · 0 citations

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