Kcnv2 E151X Mouse Captures Hallmarks of KCNV2-Associated Retinal Dystrophy.
Kcnv2 mutant mice showed markedly reduced photopic responses and reproduced the supernormal rod phenotype described in affected individuals, and this model provides a relevant platform for mechanistic studies and preclinical evaluation of gene-based or pharmacological therapies targeting cone and rod photoreceptor dysf...
Nermina Xhaferri, S. Biswas, Benjamin Davies et al.
· Clinical and Experimental Op... · 0 citations