Design, Characterization, and Efficacy of ASEnd: A Novel Chimeric Endolysin for Targeting Methicillin-Resistant Staphylococcus aureus.
The emergence of antibiotic-resistant pathogens, particularly methicillin-resistant Staphylococcus aureus (MRSA), represents a major public health threat, with limited treatment options. Bacteriophage-derived endolysins and their engineered chimeric derivatives have attracted attention as alternative antibacterial agen...