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S. Menegatti

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#protein folding Open access Oct 2026

Serotype-Tailored Midstream and Downstream Operations to Advance the Manufacturing of Adeno-Associated Viral Vectors.

Adeno-associated viruses (AAVs) are the leading vectors for in vivo gene therapy, fueling a growing demand for scalable and robust biomanufacturing processes. Yet, the impact of cell lysis conditions on the performance of midstream and downstream unit operations across serotypes remains poorly characterized. This study...

Arianna Minzoni, Shriarjun Shastry, Eduardo Barbieri et al. · 0 citations
Open access Sep 2026

Peptide ligands targeting GP64 for the purification of Baculovirus from insect cell lysates.

The first peptide affinity ligands targeting the baculoviral envelope glycoprotein GP64 for the purification of active Baculovirus particles are introduced, establishing SB4-POROS as a promising technology with a favorable projected cost structure for Baculovirus purification.

Will Smith, S. Sripada, Yuxuan Wu et al. · 0 citations

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