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Open access Sep 2026

The influence of anti-CD20-directed B cell depletion across different agents on Epstein-Barr virus-specific humoral and cellular immunity in patients with multiple sclerosis

Epidemiological evidence has established a central role of Epstein-Barr virus (EBV) in the pathogenesis of multiple sclerosis (MS). While EBV-specific T-cell responses may influence disease progression, the impact of anti-CD20 B-cell depletion therapy (BCDT) on EBV-specific cellular and humoral immunity remains insuffi...

Jakob Stögbauer, S. Bronder, Niklas Saenz Kämpfer et al. · 0 citations
Review Open access Aug 2026

AKI as a systemic syndrome and its impact on other organ systems

Acute kidney injury (AKI) affects approximately 15% of all hospitalized individuals and nearly half of those admitted to intensive care units and is increasingly recognized as a systemic syndrome whose consequences extend well beyond structural and functional changes confined to the kidney. Experimental studies highlig...

Benedetta Manca, L. Forni, Hendrik Booke et al. · 0 citations
Open access Aug 2026

Exploring serum biomarkers in paediatric psychiatry: the impact of NfL and GFAP

The findings suggest that neuroaxonal and astrocytic stress is a component of adolescent psychopathology, particularly in AN, and sNfL appears sensitive to starvation-related neurobiological changes, with levels normalizing alongside weight restoration.

Marc Pawlitzki, L. Masanneck, L. Schlarbaum et al. · 0 citations
Jan 2026

Neurofilament-Leichtkette (sNfL) als Instrument zur Beurteilung der Krankheitsaktivität und des Therapieansprechens bei Multipler Sklerose (MS)

This review addresses measurement methods (SiMoA, automated platforms), pre-analytics/matrix effects, and central confounders (esp. age, BMI/volume of distribution, renal function, intercurrent events), emphasizing standardization via age- and BMI-corrected reference data using Z-scores or percentiles.

Hernan Inojosa, K. Akgün, L. Masanneck et al. · 0 citations

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