Measles remains a significant source of morbidity and mortality globally. There are currently no licensed treatments for patients at high risk of severe disease. There is limited knowledge about the human antibody response to a measles infection or vaccination or the structural determinants of antibody-mediated neutral...
Laura S. Handal, E. Binshtein, Nurgun Kose et al.· Cell Reports Medicine· 0 citations
Pleural mesothelioma (PM) is a rare and aggressive cancer with limited treatment options and poor prognosis. Unlike other thoracic cancers responding well to immunotherapy, PM typically lacks key predictive biomarkers such as Programmed Death-Ligand 1 (PD-L1) tumor expression. Nonetheless, immune checkpoint inhibitors...
L. Cerbone, Alessia Garau, Andrea Balossino et al.· Frontiers in Immunology· 0 citations
A compartmentalized metabolic structure is proposed in which inner segment mitochondria, aerobic glycolysis, and a putative ectopic oxidative phosphorylation system in the outer segment in a triple metabolic mechanism, to supply their localized and divergent ATP demands.
R. Funk, M. Bruschi, L. Musante et al.· Progress in retinal and eye...· 0 citations
G germline revertant analysis of the COV2-3731 mAb provided additional insights into how this COV2-3731 and other IGHV3-53/3-66-encoded public antibodies evolve to gain breadth against antigenically distinct SARS-CoV-2 variants such as BA.2.3.2, BA.3.1, KP.2.2, and, to some extent, KP.3.3.2.
Naveenchandra Suryadevara, Seth J. Zost, John M. Powers et al.· bioRxiv· 0 citations
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