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Author

S. Ryhänen

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2 papers indexed here

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Open access Sep 2026

Immunotherapy refractoriness and early post-alloHCT relapse define ultra-high-risk B-ALL after CD19 CAR T-cell therapy.

CD19-directed CAR T-cell therapy (CART19) has transformed relapsed/refractory (R/R) B-cell acute lymphoblastic leukemia (B-ALL) management, but the prognostic impact of immunotherapy sensitivity and post-allogeneic hematopoietic cell transplantation (alloHCT) relapse timing in real-world practice remains unclear. We re...

V. Ortíz-Maldonado, J. Galimard, Giorgio Ottaviano et al. · 0 citations
Case report Open access Sep 2026

Neurofibromatosis 1 (NF1) gene testing reveals rising variant allele fraction as an early warning sign of juvenile myelomonocytic leukemia.

Molecular analysis of the NF1 gene is part of the diagnostic criteria for neurofibromatosis type 1 (NF1) and is particularly useful in young children who do not yet exhibit sufficient clinical signs for diagnosis. Juvenile myelomonocytic leukemia (JMML) is a rare pediatric myelodysplastic/myeloproliferative neoplasm th...

S. Peltonen, Christian Johansson, Marika H. Grönroos et al. · 0 citations

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