A modular lentiviral system for multiplexed gene perturbation and functional analysis suggests interdependence of hormone receptors in breast cancer growth in vivo
A modular, doxycycline-inducible vector system that integrates gene overexpression, shRNA-mediated knockdown, and CRISPR/Cas9-mediated regulation within a single, lentivirus-compatible system that expands the experimental repertoire for dynamic, multigene interrogation in complex systems.
Seher Alam, Daria Matvienko, Johan Boström et al.
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