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Sairos Ghniem

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#gene editing Open access Oct 2026

Pan-Cancer APOBEC Mutagenesis, Immune Microenvironment, and Clinical Outcome: A Comprehensive Multi-Omics Analysis of All Ten Family Members Across 9653 TCGA Tumors

The apolipoprotein B mRNA-editing catalytic polypeptide-like (APOBEC) family comprises ten cytidine deaminases implicated in cancer mutagenesis, yet their broader biological significance remains incompletely understood. We performed an integrated pan-cancer analysis of all ten APOBEC family members across 9653 tumors f...

Sairos Ghniem, I. Georgakopoulos-Soares, A. Zaravinos · 0 citations

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