Ribosomal RNA modification enzymes increase cellular fitness, but it’s little known whether this benefit arises from rRNA modification or a chaperone function of the modification enzyme. Here, we show that E. coli methyltransferase RsmB chaperones the initial recruitment of ribosomal proteins to the 16S 3′ domain rRNA,...
Qi-Lang Wei, Sarah A. Woodson· Science Advances· 0 citations
OBJECTIVE
This study was undertaken to establish expert consensus clinical and diagnostic criteria for ring chromosome 20 syndrome using a modified electronic Delphi process.
METHODS
In this modified two-round electronic Delphi consensus study, international experts rated candidate statements using a 9-point Likert s...
A. Sánchez-Feliciano, William D. James, Mark P. Fitzgerald et al.· Epilepsia· 0 citations
This Perspective proposes dynamic, reversible assembly as a framework for understanding the mechanisms of RNA processing and gene regulation, and shows how molecular interactions are governed by rates rather than by equilibrium affinities, providing a foundation for time-integrated structure-function studies.
Alexander Johnson-Buck, Adrien Chauvier, A. Abidi et al.· Nature reviews. Molecular ce...· 0 citations
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