#protein folding
Sep 2026
Design of a high-affinity IL-21 decoy receptor as a novel therapeutic strategy for autoimmune disorders.
Elevated levels of the pro-inflammatory cytokine Interleukin 21 (IL-21) contribute to the progression of autoimmune and inflammatory diseases by binding to its receptor (IL-21R) and activating detrimental signaling pathways in immune cells. Consequently, we developed a recombinant decoy receptor protein designed to com...
Sara Vazifeshenas, Z. Hajihassan, Seyed Shahriar Arab et al.
· Journal of Biomolecular Stru... · 0 citations