Author

Shi-Qi Tang

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Open access Sep 2026

Deciphering the Genetic Underpinnings of Liver Cirrhosis–Heart Failure Comorbidity Through Multi-Omics: CRIM1 as a Key Endothelial Mediator

An integrative multi-omics pipeline encompassing GWAS meta-analysis, gsMap-based spatial transcriptomic projection, GeneEnrich functional annotation, single-cell atlas construction, seismicGWAS and ECLIPSER cell-type scoring, eCAVIAR and fastenloc colocalization, hdWGCNA network inference, scTenifoldKnk in silico gene...

Rui-Qi Zhao, Jie Guo, Meng-Yao Han et al. · International Journal of Mol... · 0 citations

Jul 2026

The Single Amino Acid Substitution in WcaJ(Ser332Leu) Promotes Hypervirulent Klebsiella Pneumoniae Resistant to Bacteriophage and Virulence Attenuated.

This investigation investigated the phage-host interaction between phage vB_LZ2044 and hvKP strain NTUH-K2044, yielding a phage-resistant mutant PR_K2044, providing critical insights for optimizing phage-based therapeutic strategies against multidrug-resistant pathogens.

Lingrui Shi, Zhen Li, Li Xiang et al. · Probiotics and Antimicrobial... · 0 citations