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Open access Aug 2026

Multidimensional telomere diversity and inheritance at individual and population scales

Variation in telomere length, sequence composition and epigenetic state influences genome stability, aging and disease, yet its high-resolution characterization across species remains challenging. Here we present TeloXplorer, a computational framework for long-read data that jointly profiles telomere length, telomere v...

Huihui Li, Congying Chen, Lu-Dong Yang et al. · 0 citations
#protein folding Open access Sep 2026

A Generic Numbering Scheme for TMEM16 Scramblases

A generic numbering scheme for TMEM16 scramblases (GNS-TMEM16), modeled on the Ballesteros & Weinstein system established for class A G protein-coupled receptors, is introduced, bringing to light the advantages of corresponding residues identification in different TMEM16 proteins and show that the mammalian scramblase...

Shuai Yan, H. Weinstein · 0 citations

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