Open access
Aug 2026
ABTB1, as an E3 ubiquitin ligase, suppresses Th17 cell differentiation and mitigates autoimmune inflammation by promoting STAT3 ubiquitination and degradation
The research demonstrates the critical role of ABTB1 in regulating the differentiation and function of Th17 cells under conditions of autoimmune diseases and may represent a potential therapeutic target for inflammatory bowel disease (IBD) and other autoimmune disorders.
Fei Xu, Shuang Zhao, Yan Jiang et al.
· Cellular & Molecular Immunol... · 0 citations