Sep 2026
7-Ketocholesterol-induced oxidative stress impairs insulin secretion in pancreatic β-cells.
It is suggested that elevated 7-ketocholesterol is associated with β-cell dysfunction in T2D patients and appears to impair insulin secretion by inducing oxidative stress in pancreatic β-cells, positioning 7-ketocholesterol as a potential contributor to diabetes progression.
Wen-Jing Zhang, Jia-Hua Wu, Yu-Chen Zhao et al.
· Acta Diabetologica · 0 citations