The Impact of Age, Comorbidity, and Current Medication Use on Plasma p-tau217 in Adolescents: A Pilot Study.
BACKGROUND Adolescence is a critical period of neurodevelopment with the emergence of chronic medical conditions and increasing exposure to long-term medications. Phosphorylated tau at threonine 217 (p-tau217) is a sensitive blood-based biomarker of neuropathology in older adults, yet its developmental behavior and sus...